ABSTRACT
Radon [[222]Rn] Measurement in the residential environments is very important because of its effecting on human health and causing cancer in the respiratory system. [222]Rn is individually responsible for half of the natural radiation received in humans and influences on human by breathing. Hence, this study was undertaken to access the [222]Rn level in the dormitories of Kerman university of medical science [southeast of Iran] to ensure its safety level. In this study, for measuring [222]Rn level in seven dormitories of the Kerman University of Medical Sciences, the Lucas cell technique was used. This study was undertaken during the winter because of the high concentration of radon in this season due to closed building ambience. In this study, the highest measured radon gas rate was 24.5 Bq/m[3] in Boustan [1]. Average concentrations of the radon gas in all dormitories were 4.7 Bq/m[3], which is lower than the standard level. The results of this study showed that the [222]Rn level in all dormitories was lower than the normal amount [48 Bq/m3] as well as the standard level
ABSTRACT
In this study with the aim of benefiting from non-laser sources in photodynamic therapy, photo and radio sensitivity of indocyanine green as a sensitizer in photodynamic and radiation therapies were investigated. Based on the broad absorption peak of indocyanine green and using non-coherent light, the experiments were performed on human cells derived from breast cancer and melanoma. To investigate chemical, optical and radiational cytotoxicity and also photosensitivity and radiosensitivity of indocyanine green, different dozes of this material were examined. After 24 h of incubation of cells with indocyanine green, independent treatment groups were exposed to 730 +/- 20 nm light with power densities of 30, 60, and 108 J/cm[2] and 100 kVp x-ray [2 and 4 Gy]. The effect of therapy on cells was determined by MTT test. Indocyanine green showed no significant cytotoxicity. It had a good efficiency for photodynamic therapy using non-coherent sources in the wavelength of 730 +/- 20 nm, and the efficiency of treatment was dependent on the dosage of light. No significant relation between indocyanine green and radiation was observed. According to the findings, indocyanine green can be used as a photosensitizer in the range of 730 +/- 20 nm. Since there was no significant difference between groups which received both radiation and drug and those which received only radiation, indocyanine green cannot be considered as a radiosensitizer